Antibiotic-Antimycotic is widely employed in cell and tissue culture to safeguard against microbial contamination, including Gram-positive and Gram-negative bacteria, yeast, and fungi. The formulation includes three key components—penicillin, streptomycin, and amphotericin B—ensuring broad antimicrobial coverage.
Penicillin disrupts bacterial cell wall synthesis, leading to cell lysis. Streptomycin impairs protein production in prokaryotes by halting early ribosomal activity and inducing translation errors. Amphotericin B binds to sterols in fungal membranes, creating pores that allow cellular contents to leak out, ultimately compromising membrane integrity.
